For intracytoplasmic sperm injection (ICSI) technique, each suitable mature egg is injected with a single prepared sperm cell by a micropipette needle into the cytoplasm of the egg. This procedure so it bypasses all the natural barriers that the sperm has to encounter. After that the rest of the process is the same as the IVF procedure.
ICSI is appropriate in several circumstances. Most commonly when the male partner has too few sperm for conventional IVF. It is also suitable for low sperm motility and high numbers of abnormal sperm. In situations where the male partner, following vasectomy reversal, has high levels of anti-sperm antibodies, ICSI is possible. Lastly, when previous IVF attempts have been unsuccessful, ICSI can increase the likelihood of fertilization.
ICSI is appropriate in several circumstances. Most commonly when the male partner has too few sperm. However, ICSI may cause damage to eggs during the procedure but this occurs in less than 5% of injected eggs and these damaged eggs are never used in treatment.